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Category:Georgia (country) culture
Category:Northern Region (Ghana)
Category:Government agencies established in 1828
Category:1828 establishments in the British EmpireMen and women differ considerably in their reproductive biology, behavior, and physiology and it is therefore not surprising that any investigations of neurobiology that draw upon the laboratory rat as a model are by necessity different from those in which the monkey or other primate species is the starting point. This fact not only necessitates the use of different methods and experimental approaches, it also brings into play a number of problems, which need to be resolved. These include, in particular, the problem of anatomical homology and the problem of species variation. There are difficulties in unequivocally determining the homology of the various anatomical arrangements in the different species, and it is a fact of great practical relevance that the relative distances between structures vary considerably between species. It is also necessary to have the species information on the actions of various neurotransmitters and biogenic amines at receptor sites, so as to allow the relative positions of these to be ascertained. A useful way of dealing with the species variations is to examine the data obtained from a number of different species. This naturally presents practical difficulties because the animal housing is expensive and the practicalities of keeping such a large number of animals at different times means that most experiments are carried out in only one or a few of the species. The outcome of this approach is that we obtain only data on the first species or a species(s) to be investigated. We need therefore a number of species so that, while the first three or four may be entered into the study in a routine manner, the later additions can be studied with the necessary degree of freedom.The use of non-native, invasive, and highly competent invaders for biological control (myxomycetes).
Invasive species have become one of the most important problems in biological resource management, not only because of their negative effects on the ecosystem, but also because of their potential to become model species for the discovery of novel pesticide and other compounds. Myxomycetes, with a wide range of parasites and pathogens of prokaryotic or eukaryotic species, have recently been proposed to act as agents of biological control due to their ability to parasitise vertebrates. However, the invasive species hypothesis (i.e. the release of non-native parasites or pathogens to control native pathogens) is still in its infancy, and thus very little research has
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Category:Presbyterianism in GhanaInduction of mitosis by herpes simplex virus type 1 early protein ICP0 in infected cells with a nonreplicating mutant.
Herpes simplex virus type 1 (HSV-1) produces a potent lytic infection that terminates in the induction of a nonreplicating phase. Re-infection triggers cell-cycle entry of the nonreplicating cells. We have used mutant HSV-1 strains to determine whether a brief course of lytic infection induces mitosis in nonreplicating cells. Cycloheximide, which blocks translational initiation of proteins, reduced the frequency of nonreplicating cells that entered S-phase, indicating that initiation of de novo protein synthesis is necessary for entry of nonreplicating cells into S-phase. Infection with HSV-1 mutants bearing deletions of ICP0, the major viral protein that reduces the host-cell permeability barrier, and early protein kinase, a virally encoded serine/threonine-protein kinase, each reduced the frequency of nonreplicating cells that entered S-phase. A similar reduction in the frequency of mitotic cells was observed when infection was conducted with an ICP0 mutant that induces a lytic infection but which lacks the ability to induce translational initiation of protein in nonreplicating cells. These results show that viral gene products other than ICP0 can induce mitosis in infected cells during the nonreplicating phase of HSV-1 infection.Q:
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